4MMS

Crystal Structure of Prefusion-stabilized RSV F Variant Cav1 at pH 5.5

Summary for 4MMS

Entry DOI	10.2210/pdb4mms/pdb
Related	4JHW 4MMQ 4MMR 4MMT 4MMU 4MMV
Descriptor	Fusion glycoprotein F2, Fusion glycoprotein F1 fused with Fibritin trimerization domain, SULFATE ION, ... (4 entities in total)
Functional Keywords	fusion, membrane, viral protein
Biological source	Human respiratory syncytial virus A2 More
Cellular location	Virion membrane; Single-pass type I membrane protein: P03420 Virion : P10104
Total number of polymer chains	6
Total formula weight	165722.17
Authors	Mclellan, J.S.,Joyce, M.G.,Stewart-Jones, G.B.E.,Sastry, M.,Yang, Y.,Graham, B.S.,Kwong, P.D. (deposition date: 2013-09-09, release date: 2013-11-20, Last modification date: 2023-09-20)
Primary citation	McLellan, J.S.,Chen, M.,Joyce, M.G.,Sastry, M.,Stewart-Jones, G.B.,Yang, Y.,Zhang, B.,Chen, L.,Srivatsan, S.,Zheng, A.,Zhou, T.,Graepel, K.W.,Kumar, A.,Moin, S.,Boyington, J.C.,Chuang, G.Y.,Soto, C.,Baxa, U.,Bakker, A.Q.,Spits, H.,Beaumont, T.,Zheng, Z.,Xia, N.,Ko, S.Y.,Todd, J.P.,Rao, S.,Graham, B.S.,Kwong, P.D. Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus. Science, 342:592-598, 2013 Cited by PubMed: 24179220 DOI: 10.1126/science.1243283 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.397 Å)

Structure validation