4MLB
Reverse polarity of binding pocket suggests different function of a MOP superfamily transporter from Pyrococcus furiosus Vc1 (DSM3638)
Summary for 4MLB
| Entry DOI | 10.2210/pdb4mlb/pdb |
| Descriptor | PF0708, PENTAETHYLENE GLYCOL MONODECYL ETHER, CHLORIDE ION, ... (4 entities in total) |
| Functional Keywords | lipid translocase, flippase, membrane protein, transport protein |
| Biological source | Pyrococcus furiosus |
| Total number of polymer chains | 4 |
| Total formula weight | 231846.29 |
| Authors | Malviya, V.N.,Nonaka, T.,Muenke, C.,Koepke, J.,Michel, H. (deposition date: 2013-09-06, release date: 2013-09-25, Last modification date: 2023-09-20) |
| Primary citation | Zakrzewska, S.,Mehdipour, A.R.,Malviya, V.N.,Nonaka, T.,Koepke, J.,Muenke, C.,Hausner, W.,Hummer, G.,Safarian, S.,Michel, H. Inward-facing conformation of a multidrug resistance MATE family transporter. Proc.Natl.Acad.Sci.USA, 116:12275-12284, 2019 Cited by PubMed: 31160466DOI: 10.1073/pnas.1904210116 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.349 Å) |
Structure validation
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