4LZG

Binary complex of human DNA Polymerase Mu with DNA

Summary for 4LZG

Entry DOI	10.2210/pdb4lzg/pdb
Related	2IHM 4LZD 4M04 4M0A
Descriptor	DNA-directed DNA/RNA polymerase mu, template strand, upstream primer strand, ... (8 entities in total)
Functional Keywords	polymerase, dna break repair, transferase-dna complex, transferase/dna
Biological source	Homo sapiens (human) More
Cellular location	Nucleus (By similarity): Q9NP87
Total number of polymer chains	4
Total formula weight	45386.87
Authors	Moon, A.F.,Pryor, J.M.,Ramsden, D.A.,Kunkel, T.A.,Bebenek, K.,Pedersen, L.C. (deposition date: 2013-07-31, release date: 2014-02-05, Last modification date: 2024-04-03)
Primary citation	Moon, A.F.,Pryor, J.M.,Ramsden, D.A.,Kunkel, T.A.,Bebenek, K.,Pedersen, L.C. Sustained active site rigidity during synthesis by human DNA polymerase mu. Nat.Struct.Mol.Biol., 21:253-260, 2014 Cited by PubMed: 24487959 DOI: 10.1038/nsmb.2766 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.599 Å)

Structure validation