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4LZG

Binary complex of human DNA Polymerase Mu with DNA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA-directed DNA/RNA polymerase mupolymer35640054.41UniProt (Q9NP87)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
Homo sapiens (human)Pol Mu, Terminal transferase
2B
(T)
template strandpolymer92740.81
3C
(P)
upstream primer strandpolymer41190.81
4D
(D)
downstream primer strandpolymer41191.81
5E
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
6F, I
(A)
CHLORIDE IONnon-polymer35.52Chemie (CL)
7G, H
(A)
SODIUM IONnon-polymer23.02Chemie (NA)
8J, K, L, M
(A, T, P, D)
waterwater18.0513Chemie (HOH)
Sequence modifications
A: 132 - 494 (UniProt: Q9NP87)
PDBExternal DatabaseDetails
Gly 127-expression tag
Ser 128-expression tag
Ala 129-expression tag
Ala 130-expression tag
Ala 131-expression tag
-Pro 398deletion
-Gly 399deletion
-Ala 400deletion
-Ala 401deletion
-Val 402deletion
-Gly 403deletion
-Gly 404deletion
-Ser 405deletion
-Thr 406deletion
-Arg 407deletion
-Pro 408deletion
-Cys 409deletion
-Pro 410deletion
Gly 410-insertion
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight45177.9
Non-Polymers*Number of molecules5
Total formula weight209.0
All*Total formula weight45386.9
*Water molecules are not included.

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PDB entries from 2025-06-18

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