4LXR
Structure of the Toll - Spatzle complex, a molecular hub in Drosophila development and innate immunity
Summary for 4LXR
Entry DOI | 10.2210/pdb4lxr/pdb |
Related | 3e07 4LXS |
Descriptor | Protein toll, Protein spaetzle C-106, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total) |
Functional Keywords | tlr, leucine-rich repeat, immune system, cytokine receptor, embryonic development, innate immunity, receptor-ligand complex', immune system-cytokine complex, immune system/cytokine |
Biological source | Drosophila melanogaster (Fruit fly) More |
Total number of polymer chains | 3 |
Total formula weight | 119557.35 |
Authors | Stelter, M.,Parthier, C.,Breithaupt, C.,Stubbs, M.T. (deposition date: 2013-07-30, release date: 2014-04-09, Last modification date: 2020-07-29) |
Primary citation | Parthier, C.,Stelter, M.,Ursel, C.,Fandrich, U.,Lilie, H.,Breithaupt, C.,Stubbs, M.T. Structure of the Toll-Spatzle complex, a molecular hub in Drosophila development and innate immunity. Proc.Natl.Acad.Sci.USA, 111:6281-6286, 2014 Cited by PubMed: 24733933DOI: 10.1073/pnas.1320678111 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
Download full validation report