4LRL

Structure of an Enterococcus Faecalis HD-domain protein complexed with dGTP and dTTP

Summary for 4LRL

Entry DOI	10.2210/pdb4lrl/pdb
Related	2O6I 3IRH
Descriptor	HD domain protein, NICKEL (II) ION, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... (7 entities in total)
Functional Keywords	structural genomics, psi-2, protein structure initiative, midwest center for structural genomics, mcsg, hd domain, phosphohydrolase, dntpase, allosteric regulation, metal binding protein, hydrolase
Biological source	Enterococcus faecalis
Total number of polymer chains	4
Total formula weight	227342.39
Authors	Vorontsov, I.I.,Minasov, G.,Shuvalova, L.,Joachimiak, A.,Anderson, W.F.,Midwest Center for Structural Genomics (MCSG) (deposition date: 2013-07-19, release date: 2013-11-20, Last modification date: 2023-09-20)
Primary citation	Vorontsov, I.I.,Wu, Y.,Delucia, M.,Minasov, G.,Mehrens, J.,Shuvalova, L.,Anderson, W.F.,Ahn, J. Mechanisms of Allosteric Activation and Inhibition of the Deoxyribonucleoside Triphosphate Triphosphohydrolase from Enterococcus faecalis. J.Biol.Chem., 289:2815-2824, 2014 Cited by PubMed: 24338016 DOI: 10.1074/jbc.M113.524207 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.35 Å)

Structure validation