3IRH

Structure of an Enterococcus Faecalis HD-domain protein complexed with dGTP and dATP

Summary for 3IRH

• Entry DOI: 10.2210/pdb3irh/pdb
• Related: 2O6I
• Descriptor: HD domain protein, CALCIUM ION, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: hd domain, phosphohydrolase, dntpase, structural genomics, psi-2, protein structure initiative, midwest center for structural genomics, mcsg, unknown function, hydrolase
• Biological source: Enterococcus faecalis (Streptococcus faecalis)
• Total number of polymer chains: 4
• Total formula weight: 226715.43

Authors

Vorontsov, I.I.,Minasov, G.,Shuvalova, L.,Brunzelle, J.S.,Joachimiak, A.,Anderson, W.F.,Midwest Center for Structural Genomics (MCSG) (deposition date: 2009-08-24, release date: 2009-09-22, Last modification date: 2023-09-06)

• Primary citation: Vorontsov, I.I.,Minasov, G.,Kiryukhina, O.,Brunzelle, J.S.,Shuvalova, L.,Anderson, W.F.; Characterization of the deoxynucleotide triphosphate triphosphohydrolase (dNTPase) activity of the EF1143 protein from Enterococcus faecalis and crystal structure of the activator-substrate complex.; J.Biol.Chem., 286:33158-33166, 2011; PubMed: 21757692; DOI: 10.1074/jbc.M111.250456

Experimental method

X-RAY DIFFRACTION (2.4 Å)