4LRL

Structure of an Enterococcus Faecalis HD-domain protein complexed with dGTP and dTTP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0006203	biological_process	dGTP catabolic process
A	0008832	molecular_function	dGTPase activity
A	0046872	molecular_function	metal ion binding
B	0000166	molecular_function	nucleotide binding
B	0006203	biological_process	dGTP catabolic process
B	0008832	molecular_function	dGTPase activity
B	0046872	molecular_function	metal ion binding
C	0000166	molecular_function	nucleotide binding
C	0006203	biological_process	dGTP catabolic process
C	0008832	molecular_function	dGTPase activity
C	0046872	molecular_function	metal ion binding
D	0000166	molecular_function	nucleotide binding
D	0006203	biological_process	dGTP catabolic process
D	0008832	molecular_function	dGTPase activity
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NI A 501

Chain	Residue
A	HIS66
A	HIS110
A	ASP111
A	ASP183
A	HOH651
A	HOH801

---

site_id	AC2
Number of Residues	16
Details	BINDING SITE FOR RESIDUE DGT A 502

Chain	Residue
A	ILE35
A	ASN36
A	GLN41
A	ARG44
A	PHE64
A	HOH841
B	PHE54
B	THR55
B	ARG326
B	LYS330
B	HOH729
B	HOH737
B	HOH780
A	LYS14
A	VAL15
A	PHE16

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE TRS A 503

Chain	Residue
A	ASP318
A	ARG322
A	PHE356
A	TYR361
A	HOH796

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NI B 501

Chain	Residue
B	HIS66
B	HIS110
B	ASP111
B	ASP183
B	HOH742
B	HOH786

---

site_id	AC5
Number of Residues	15
Details	BINDING SITE FOR RESIDUE DGT B 502

Chain	Residue
A	PHE54
A	THR55
A	VAL247
A	ARG326
A	LYS330
A	HOH677
B	LYS14
B	VAL15
B	PHE16
B	ASN36
B	GLN41
B	ARG44
B	PHE64
B	TTP503
B	HOH749

---

site_id	AC6
Number of Residues	17
Details	BINDING SITE FOR RESIDUE TTP B 503

Chain	Residue
A	THR55
A	PHE56
A	GLN241
A	HIS245
A	HOH630
A	HOH652
A	HOH677
A	HOH729
A	HOH764
A	HOH815
B	VAL15
B	ARG17
B	DGT502
D	ARG206
D	ARG209
D	ASN223
D	HOH702

---

site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MLI B 504

Chain	Residue
B	GLU7

---

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE TRS B 505

Chain	Residue
B	ASP318
B	PHE356
B	HOH787

---

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE TRS B 506

Chain	Residue
B	GLN135
B	PHE288

---

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NI C 501

Chain	Residue
C	HIS66
C	HIS110
C	ASP111
C	ASP183
C	HOH747
C	HOH756

---

site_id	BC2
Number of Residues	17
Details	BINDING SITE FOR RESIDUE DGT C 502

Chain	Residue
C	LYS14
C	VAL15
C	PHE16
C	ILE35
C	ASN36
C	GLN41
C	ARG44
C	PHE64
D	PHE54
D	THR55
D	VAL247
D	ARG326
D	LYS330
D	LYS422
D	HOH675
D	HOH716
D	HOH718

---

site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MLI C 503

Chain	Residue
C	VAL354
C	GLY355
C	PHE356
C	TYR361
C	HOH730

---

site_id	BC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NI D 501

Chain	Residue
D	HIS66
D	HIS110
D	ASP111
D	ASP183
D	HOH698
D	HOH725

---

site_id	BC5
Number of Residues	17
Details	BINDING SITE FOR RESIDUE DGT D 502

Chain	Residue
C	PHE54
C	THR55
C	VAL247
C	ARG326
C	LYS330
C	LYS422
C	HOH713
C	HOH724
D	LYS14
D	VAL15
D	PHE16
D	ASN36
D	GLN41
D	ARG44
D	PHE64
D	TTP503
D	HOH601

---

site_id	BC6
Number of Residues	14
Details	BINDING SITE FOR RESIDUE TTP D 503

Chain	Residue
B	ARG206
B	ARG209
B	HOH664
C	THR55
C	PHE56
C	GLN241
C	HIS245
C	HOH641
C	HOH699
C	HOH711
D	VAL15
D	ARG17
D	DGT502
D	HOH601

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