4LRL
Structure of an Enterococcus Faecalis HD-domain protein complexed with dGTP and dTTP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0006203 | biological_process | dGTP catabolic process |
| A | 0008832 | molecular_function | dGTPase activity |
| A | 0045088 | biological_process | regulation of innate immune response |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051607 | biological_process | defense response to virus |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0006203 | biological_process | dGTP catabolic process |
| B | 0008832 | molecular_function | dGTPase activity |
| B | 0045088 | biological_process | regulation of innate immune response |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051607 | biological_process | defense response to virus |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0006203 | biological_process | dGTP catabolic process |
| C | 0008832 | molecular_function | dGTPase activity |
| C | 0045088 | biological_process | regulation of innate immune response |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0051607 | biological_process | defense response to virus |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0006203 | biological_process | dGTP catabolic process |
| D | 0008832 | molecular_function | dGTPase activity |
| D | 0045088 | biological_process | regulation of innate immune response |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0051607 | biological_process | defense response to virus |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NI A 501 |
| Chain | Residue |
| A | HIS66 |
| A | HIS110 |
| A | ASP111 |
| A | ASP183 |
| A | HOH651 |
| A | HOH801 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE DGT A 502 |
| Chain | Residue |
| A | ILE35 |
| A | ASN36 |
| A | GLN41 |
| A | ARG44 |
| A | PHE64 |
| A | HOH841 |
| B | PHE54 |
| B | THR55 |
| B | ARG326 |
| B | LYS330 |
| B | HOH729 |
| B | HOH737 |
| B | HOH780 |
| A | LYS14 |
| A | VAL15 |
| A | PHE16 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE TRS A 503 |
| Chain | Residue |
| A | ASP318 |
| A | ARG322 |
| A | PHE356 |
| A | TYR361 |
| A | HOH796 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NI B 501 |
| Chain | Residue |
| B | HIS66 |
| B | HIS110 |
| B | ASP111 |
| B | ASP183 |
| B | HOH742 |
| B | HOH786 |
| site_id | AC5 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE DGT B 502 |
| Chain | Residue |
| A | PHE54 |
| A | THR55 |
| A | VAL247 |
| A | ARG326 |
| A | LYS330 |
| A | HOH677 |
| B | LYS14 |
| B | VAL15 |
| B | PHE16 |
| B | ASN36 |
| B | GLN41 |
| B | ARG44 |
| B | PHE64 |
| B | TTP503 |
| B | HOH749 |
| site_id | AC6 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE TTP B 503 |
| Chain | Residue |
| A | THR55 |
| A | PHE56 |
| A | GLN241 |
| A | HIS245 |
| A | HOH630 |
| A | HOH652 |
| A | HOH677 |
| A | HOH729 |
| A | HOH764 |
| A | HOH815 |
| B | VAL15 |
| B | ARG17 |
| B | DGT502 |
| D | ARG206 |
| D | ARG209 |
| D | ASN223 |
| D | HOH702 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE MLI B 504 |
| Chain | Residue |
| B | GLU7 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE TRS B 505 |
| Chain | Residue |
| B | ASP318 |
| B | PHE356 |
| B | HOH787 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE TRS B 506 |
| Chain | Residue |
| B | GLN135 |
| B | PHE288 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NI C 501 |
| Chain | Residue |
| C | HIS66 |
| C | HIS110 |
| C | ASP111 |
| C | ASP183 |
| C | HOH747 |
| C | HOH756 |
| site_id | BC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE DGT C 502 |
| Chain | Residue |
| C | LYS14 |
| C | VAL15 |
| C | PHE16 |
| C | ILE35 |
| C | ASN36 |
| C | GLN41 |
| C | ARG44 |
| C | PHE64 |
| D | PHE54 |
| D | THR55 |
| D | VAL247 |
| D | ARG326 |
| D | LYS330 |
| D | LYS422 |
| D | HOH675 |
| D | HOH716 |
| D | HOH718 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MLI C 503 |
| Chain | Residue |
| C | VAL354 |
| C | GLY355 |
| C | PHE356 |
| C | TYR361 |
| C | HOH730 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NI D 501 |
| Chain | Residue |
| D | HIS66 |
| D | HIS110 |
| D | ASP111 |
| D | ASP183 |
| D | HOH698 |
| D | HOH725 |
| site_id | BC5 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE DGT D 502 |
| Chain | Residue |
| C | PHE54 |
| C | THR55 |
| C | VAL247 |
| C | ARG326 |
| C | LYS330 |
| C | LYS422 |
| C | HOH713 |
| C | HOH724 |
| D | LYS14 |
| D | VAL15 |
| D | PHE16 |
| D | ASN36 |
| D | GLN41 |
| D | ARG44 |
| D | PHE64 |
| D | TTP503 |
| D | HOH601 |
| site_id | BC6 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE TTP D 503 |
| Chain | Residue |
| B | ARG206 |
| B | ARG209 |
| B | HOH664 |
| C | THR55 |
| C | PHE56 |
| C | GLN241 |
| C | HIS245 |
| C | HOH641 |
| C | HOH699 |
| C | HOH711 |
| D | VAL15 |
| D | ARG17 |
| D | DGT502 |
| D | HOH601 |
