4LDL

Structure of beta2 adrenoceptor bound to hydroxybenzylisoproterenol and an engineered nanobody

Summary for 4LDL

• Entry DOI: 10.2210/pdb4ldl/pdb
• Related: 4LDE 4LDO
• Descriptor: Lysozyme, Beta-2 adrenergic receptor, Camelid Antibody Fragment, 4-[(1R)-1-hydroxy-2-{[1-(4-hydroxyphenyl)-2-methylpropan-2-yl]amino}ethyl]benzene-1,2-diol, ... (6 entities in total)
• Functional Keywords: g protein coupled receptor, membrane protein-hydrolase complex, membrane protein/hydrolase
• Biological source: Enterobacteria phage T4; More
• Cellular location: Cell membrane ; Multi- pass membrane protein : P07550
• Total number of polymer chains: 2
• Total formula weight: 67061.22

Authors

Ring, A.M.,Manglik, A.,Kruse, A.C.,Enos, M.D.,Weis, W.I.,Garcia, K.C.,Kobilka, B.K. (deposition date: 2013-06-24, release date: 2013-09-25, Last modification date: 2023-09-20)

• Primary citation: Ring, A.M.,Manglik, A.,Kruse, A.C.,Enos, M.D.,Weis, W.I.,Garcia, K.C.,Kobilka, B.K.; Adrenaline-activated structure of beta 2-adrenoceptor stabilized by an engineered nanobody.; Nature, 502:575-579, 2013; PubMed: 24056936; DOI: 10.1038/nature12572

Experimental method

X-RAY DIFFRACTION (3.1 Å)