4KVG

Crystal structure of RIAM RA-PH domains in complex with GTP bound Rap1

Summary for 4KVG

Entry DOI	10.2210/pdb4kvg/pdb
Descriptor	Ras-related protein Rap-1A, Amyloid beta A4 precursor protein-binding family B member 1-interacting protein, GUANOSINE-5'-TRIPHOSPHATE, ... (6 entities in total)
Functional Keywords	ras-related protein, ubiquitin fold, gtpase, actin polymerization, integrin activation, cell adhesion, riam, rapl, mst1, pdk, rap1, ena/vasp, profilin, membrane, signaling protein
Biological source	Homo sapiens (human) More
Cellular location	Cell membrane; Lipid-anchor: P62834 Cell membrane; Peripheral membrane protein: Q8R5A3
Total number of polymer chains	4
Total formula weight	101497.81
Authors	Zhang, H.,Chang, Y.E.,Brennan, M.L.,Wu, J. (deposition date: 2013-05-22, release date: 2014-03-05, Last modification date: 2024-02-28)
Primary citation	Zhang, H.,Chang, Y.C.,Brennan, M.L.,Wu, J. The structure of Rap1 in complex with RIAM reveals specificity determinants and recruitment mechanism. J Mol Cell Biol, 6:128-139, 2014 Cited by PubMed: 24287201 DOI: 10.1093/jmcb/mjt044 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation