4KVG
Crystal structure of RIAM RA-PH domains in complex with GTP bound Rap1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Ras-related protein Rap-1A | polymer | 168 | 19236.9 | 2 | UniProt (P62834) Pfam (PF00071) In PDB | Homo sapiens (human) | C21KG, G-22K, GTP-binding protein smg p21A, Ras-related protein Krev-1 |
2 | B, D | Amyloid beta A4 precursor protein-binding family B member 1-interacting protein | polymer | 260 | 30902.5 | 2 | UniProt (Q8R5A3) Pfam (PF00788) Pfam (PF21989) Pfam (PF00169) In PDB | Mus musculus (mouse) | APBB1-interacting protein 1, Proline-rich EVH1 ligand 1, PREL-1, Proline-rich protein 48 |
3 | A, C | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
4 | A, C | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
5 | B, D | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
6 | water | water | 18.0 | 725 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 167 (UniProt: P62834)
B, D: 179 - 437 (UniProt: Q8R5A3)
PDB | External Database | Details |
---|---|---|
His 0 | - | expression tag |
Val 12 | Gly 12 | engineered mutation |
Glu 63 | Gln 63 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Met 178 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 100278.7 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 1219.1 | |
All* | Total formula weight | 101497.8 |