4KM6

Human folate receptor alpha (FOLR1) at acidic pH, orthorhombic form

4KM6 の概要

• エントリーDOI: 10.2210/pdb4km6/pdb
• 関連するPDBエントリー: 4KM6 4KM7 4KMX 4KMY 4KMZ 4KN0 4KN1 4KN2
• 分子名称: Folate receptor alpha, CALCIUM ION, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: folate receptor alpha, folr1, folate receptor, folic acid, folates, 5-methyltetrahydrofolate, antifolates, folate-conjugates, gpi-anchored protein on eukaryotic membrane, transport protein, membrane protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 25026.06

構造登録者

Singh, M.,Dann III, C.E. (登録日: 2013-05-08, 公開日: 2013-08-07, 最終更新日: 2020-07-29)

• 主引用文献: Wibowo, A.S.,Singh, M.,Reeder, K.M.,Carter, J.J.,Kovach, A.R.,Meng, W.,Ratnam, M.,Zhang, F.,Dann, C.E.; Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition.; Proc.Natl.Acad.Sci.USA, 110:15180-15188, 2013; PubMed: 23934049; DOI: 10.1073/pnas.1308827110

実験手法

X-RAY DIFFRACTION (1.55 Å)