4JS0

Complex of Cdc42 with the CRIB-PR domain of IRSp53

4JS0 の概要

• エントリーDOI: 10.2210/pdb4js0/pdb
• 分子名称: Cell division control protein 42 homolog, Brain-specific angiogenesis inhibitor 1-associated protein 2, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... (6 entities in total)
• 機能のキーワード: gtpase binding domain, crib domain, cytoskeleton regulation, signaling protein-signaling protein complex, signaling protein/signaling protein
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential): P60953; Cytoplasm: Q9UQB8
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 24739.77

構造登録者

Kast, D.J.,Dominguez, R. (登録日: 2013-03-22, 公開日: 2014-03-05, 最終更新日: 2024-02-28)

• 主引用文献: Kast, D.J.,Yang, C.,Disanza, A.,Boczkowska, M.,Madasu, Y.,Scita, G.,Svitkina, T.,Dominguez, R.; Mechanism of IRSp53 inhibition and combinatorial activation by Cdc42 and downstream effectors.; Nat.Struct.Mol.Biol., 21:413-422, 2014; PubMed: 24584464; DOI: 10.1038/nsmb.2781

実験手法

X-RAY DIFFRACTION (1.9 Å)