4JS0
Complex of Cdc42 with the CRIB-PR domain of IRSp53
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cell division control protein 42 homolog | polymer | 178 | 19816.8 | 1 | UniProt (P60953) Pfam (PF00071) | Homo sapiens (human) | G25K GTP-binding protein |
| 2 | B (B) | Brain-specific angiogenesis inhibitor 1-associated protein 2 | polymer | 32 | 3288.9 | 1 | UniProt (Q9UQB8) | Homo sapiens | BAI-associated protein 2, BAI1-associated protein 2, Protein BAP2, Fas ligand-associated factor 3, FLAF3, Insulin receptor substrate p53/p58, IRS-58, IRSp53/58, Insulin receptor substrate protein of 53 kDa, IRSp53, Insulin receptor substrate p53 |
| 3 | C (A) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 1 | Chemie (GNP) | |||
| 4 | D, E (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | F, G, H (A) | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL | non-polymer | 354.4 | 3 | Chemie (PE4) | |||
| 6 | I, J (A, B) | water | water | 18.0 | 151 | Chemie (HOH) |
Sequence modifications
A: 1 - 178 (UniProt: P60953)
| PDB | External Database | Details |
|---|---|---|
| Val 12 | Gly 12 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 23105.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1634.1 | |
| All* | Total formula weight | 24739.8 |
