4J2X
CSL (RBP-Jk) with corepressor KyoT2 bound to DNA
Summary for 4J2X
Entry DOI | 10.2210/pdb4j2x/pdb |
Related | 1TTU 2FO1 3BRD 3BRF 3BRG 3IAG |
Descriptor | Recombining binding protein suppressor of hairless, Four and a half LIM domains protein 1, 5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*T)-3', ... (6 entities in total) |
Functional Keywords | lim domain containing protein, transcription factor corepressor, dna binding, nucleus, transcription-dna binding protein-dna complex, transcription/dna binding protein/dna |
Biological source | Mus musculus (mouse) More |
Cellular location | Nucleus: P31266 Isoform 1: Cytoplasm. Isoform 2: Nucleus: P97447 |
Total number of polymer chains | 8 |
Total formula weight | 120724.72 |
Authors | Collins, K.J.,Kovall, R.A. (deposition date: 2013-02-05, release date: 2013-11-06, Last modification date: 2023-09-20) |
Primary citation | Collins, K.J.,Yuan, Z.,Kovall, R.A. Structure and Function of the CSL-KyoT2 Corepressor Complex: A Negative Regulator of Notch Signaling. Structure, 22:70-81, 2014 Cited by PubMed: 24290140DOI: 10.1016/j.str.2013.10.010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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