4J2X

CSL (RBP-Jk) with corepressor KyoT2 bound to DNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Recombining binding protein suppressor of hairless	polymer	427	48225.0	2	UniProt (P31266) Pfam (PF09271) Pfam (PF09270) Pfam (PF20144)	Mus musculus (mouse)	CSL, CBF-1, Supressor of Hairless, Lag-1, J kappa-recombination signal-binding protein, RBP-J kappa
2	B, D (B, D)	Four and a half LIM domains protein 1	polymer	28	2929.3	2	UniProt (P97447)	Mus musculus (mouse)	FHL-1, KyoT, RBP-associated molecule 14-1, RAM14-1, Skeletal muscle LIM-protein 1, SLIM, SLIM-1
3	E, G (E, G)	5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*T)-3'	polymer	15	4503.9	2		Homo sapiens
4	F, H (F, H)	5'-D(*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3'	polymer	15	4673.1	2		Homo sapiens
5	I (A)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
6	J, K (A, C)	water	water		18.0	8	Chemie (HOH)

Sequence modifications

A, C: 53 - 474 (UniProt: P31266)

PDB	External Database	Details
Gly 48	-	expression tag
Pro 49	-	expression tag
Leu 50	-	expression tag
Gly 51	-	expression tag
Ser 52	-	expression tag
Thr 115	Arg 115	engineered mutation

B, D: 184 - 210 (UniProt: P97447)

PDB	External Database	Details
Ser 183	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	120662.7
Non-Polymers*	Number of molecules	1
	Total formula weight	62.1
All*	Total formula weight	120724.7

*Water molecules are not included.