4J2X
CSL (RBP-Jk) with corepressor KyoT2 bound to DNA
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Recombining binding protein suppressor of hairless | polymer | 427 | 48225.0 | 2 | UniProt (P31266) Pfam (PF09271) Pfam (PF09270) Pfam (PF20144) In PDB | Mus musculus (mouse) | CSL, CBF-1, Supressor of Hairless, Lag-1, J kappa-recombination signal-binding protein, RBP-J kappa |
2 | B, D | Four and a half LIM domains protein 1 | polymer | 28 | 2929.3 | 2 | UniProt (P97447) In PDB | Mus musculus (mouse) | FHL-1, KyoT, RBP-associated molecule 14-1, RAM14-1, Skeletal muscle LIM-protein 1, SLIM, SLIM-1 |
3 | E, G | 5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*T)-3' | polymer | 15 | 4503.9 | 2 | Homo sapiens | ||
4 | F, H | 5'-D(*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3' | polymer | 15 | 4673.1 | 2 | Homo sapiens | ||
5 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
6 | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
A, C: 53 - 474 (UniProt: P31266)
B, D: 184 - 210 (UniProt: P97447)
PDB | External Database | Details |
---|---|---|
Gly 48 | - | expression tag |
Pro 49 | - | expression tag |
Leu 50 | - | expression tag |
Gly 51 | - | expression tag |
Ser 52 | - | expression tag |
Thr 115 | Arg 115 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Ser 183 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 120662.7 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 62.1 | |
All* | Total formula weight | 120724.7 |