Crystal Structure of the CSL-Notch-Mastermind ternary complex bound to DNA

Summary for 2FO1

Descriptor5'-D(*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3', 5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*T)-3', Lin-12 and glp-1 phenotype protein 1, isoform b, ... (5 entities in total)
Functional Keywordsbeta-barrel, protein-dna complex, double helix, ankyrin repeat, gene regulation-signalling protein-dna complex, gene regulation/signalling protein/dna
Biological sourceCaenorhabditis elegans
Cellular locationNucleus Q09260
Membrane; Single-pass type I membrane protein P14585
Total number of polymer chains5
Total molecular weight115151.65
Wilson, J.J.,Kovall, R.A. (deposition date: 2006-01-12, release date: 2006-03-21, Last modification date: 2011-07-13)
Primary citation
Wilson, J.J.,Kovall, R.A.
Crystal structure of the CSL-Notch-Mastermind ternary complex bound to DNA.
Cell(Cambridge,Mass.), 124:985-996, 2006
PubMed: 16530045 (PDB entries with the same primary citation)
DOI: 10.1016/j.cell.2006.01.035
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.32758 10.0% 12.4% 2.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-11-25