2FO1
Crystal Structure of the CSL-Notch-Mastermind ternary complex bound to DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | B | 5'-D(*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3' | polymer | 15 | 4673.1 | 1 | |||
| 2 | C | 5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*T)-3' | polymer | 15 | 4503.9 | 1 | |||
| 3 | A | Lin-12 and glp-1 phenotype protein 1, isoform b | polymer | 477 | 53761.6 | 1 | GenBank (22532887) Pfam (PF09271) Pfam (PF09270) Pfam (PF20144) UniProt (by SIFTS) (V6CLJ5) In PDB | Caenorhabditis elegans | LAG-1 |
| 4 | D | Protein lag-3 | polymer | 85 | 9755.6 | 1 | UniProt (Q09260) In PDB | Caenorhabditis elegans | PROTEIN SEL-8, Abnormal germ line proliferation protein 3, Abnormal cell lineage protein 3 |
| 5 | E | Lin-12 protein | polymer | 373 | 42457.4 | 1 | UniProt (P14585) Pfam (PF00023) In PDB | Caenorhabditis elegans |
Sequence modifications
A: 192 - 663 (GenBank: 22532887)
D: 49 - 132 (UniProt: Q09260)
E: 931 - 1301 (UniProt: P14585)
| PDB | External Database | Details |
|---|---|---|
| Gly 187 | - | cloning artifact |
| Pro 188 | - | cloning artifact |
| Leu 189 | - | cloning artifact |
| Gly 190 | - | cloning artifact |
| Ser 191 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Ser 48 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Gly 929 | - | cloning artifact |
| Ser 930 | - | cloning artifact |
| Mse 939 | Met 939 | modified residue |
| Mse 946 | Met 946 | modified residue |
| Mse 949 | Met 949 | modified residue |
| Mse 1090 | Met 1090 | modified residue |
| Mse 1099 | Met 1099 | modified residue |
| Mse 1114 | Met 1114 | modified residue |
| Mse 1142 | Met 1142 | modified residue |
| Mse 1143 | Met 1143 | modified residue |
| Mse 1146 | Met 1146 | modified residue |
| Mse 1164 | Met 1164 | modified residue |
| Mse 1168 | Met 1168 | modified residue |
| Mse 1220 | Met 1220 | modified residue |
| Mse 1246 | Met 1246 | modified residue |
| Mse 1258 | Met 1258 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 115151.7 | |
| All* | Total formula weight | 115151.7 |
