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4IC8

Crystal structure of the apo ERK5 kinase domain

Summary for 4IC8
Entry DOI10.2210/pdb4ic8/pdb
Related4IC7
DescriptorMitogen-activated protein kinase 7 (1 entity in total)
Functional Keywordskinase, signaling, transferase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: Q13164
Total number of polymer chains2
Total formula weight99605.80
Authors
Gogl, G.,Remenyi, A. (deposition date: 2012-12-10, release date: 2013-02-13, Last modification date: 2024-02-28)
Primary citationGlatz, G.,Gogl, G.,Alexa, A.,Remenyi, A.
Structural mechanism for the specific assembly and activation of the extracellular signal regulated kinase 5 (ERK5) module.
J.Biol.Chem., 288:8596-8609, 2013
Cited by
PubMed: 23382384
DOI: 10.1074/jbc.M113.452235
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation

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