4IC8

Crystal structure of the apo ERK5 kinase domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Mitogen-activated protein kinase 7	polymer	442	49802.9	2	UniProt (Q13164) Pfam (PF00069)	Homo sapiens (human)	MAP kinase 7, MAPK 7, Big MAP kinase 1, BMK-1, Extracellular signal-regulated kinase 5, ERK-5

Sequence modifications

A, B: -21 - 409 (UniProt: Q13164)

PDB	External Database	Details
Gly -23	-	expression tag
Ser -22	-	expression tag
Ser 410	-	expression tag
Gly 411	-	expression tag
Arg 412	-	expression tag
His 413	-	expression tag
His 414	-	expression tag
His 415	-	expression tag
His 416	-	expression tag
His 417	-	expression tag
His 418	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	99605.8
All*	Total formula weight	99605.8

*Water molecules are not included.