4I91

Crystal Structure of Cytochrome P450 2B6 (Y226H/K262R) in complex with alpha-Pinene.

Summary for 4I91

Entry DOI	10.2210/pdb4i91/pdb
Related	3IBD 3QOA 3QU8 3UA5
Descriptor	Cytochrome P450 2B6, PROTOPORPHYRIN IX CONTAINING FE, beta-D-fructofuranose, ... (6 entities in total)
Functional Keywords	oxidoreductase, membrane protein, cyp2b6, p450, cytochrome p450 2b6, monooxygenase, endoplasmic reticulum, heme, iron, membrane, metal binding, microsome
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	57062.60
Authors	Shah, M.B.,Stout, C.D.,Halpert, J.R. (deposition date: 2012-12-04, release date: 2013-07-03, Last modification date: 2023-09-20)
Primary citation	Wilderman, P.R.,Shah, M.B.,Jang, H.H.,Stout, C.D.,Halpert, J.R. Structural and Thermodynamic Basis of (+)-alpha-Pinene Binding to Human Cytochrome P450 2B6. J.Am.Chem.Soc., 135:10433-10440, 2013 Cited by PubMed: 23786449 DOI: 10.1021/ja403042k PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation