4HVX

tRNA-guanine transglycosylase Y106F, C158V mutant in complex with queuine

Summary for 4HVX

Entry DOI	10.2210/pdb4hvx/pdb
Related	4E2V 4GCX 4GD0 4H6E 4H7Z 4HSH
Descriptor	Queuine tRNA-ribosyltransferase, ZINC ION, GLYCEROL, ... (5 entities in total)
Functional Keywords	substrate specificity, bacterial tgt, transferase, guanine exchange enzyme, queuine, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Zymomonas mobilis subsp. mobilis
Total number of polymer chains	1
Total formula weight	43524.66
Authors	Biela, I.,Tidten-Luksch, N.,Heine, A.,Reuter, K.,Klebe, G. (deposition date: 2012-11-07, release date: 2012-12-26, Last modification date: 2023-09-20)
Primary citation	Biela, I.,Tidten-Luksch, N.,Immekus, F.,Glinca, S.,Nguyen, T.X.,Gerber, H.D.,Heine, A.,Klebe, G.,Reuter, K. Investigation of Specificity Determinants in Bacterial tRNA-Guanine Transglycosylase Reveals Queuine, the Substrate of Its Eucaryotic Counterpart, as Inhibitor. Plos One, 8:e64240-e64240, 2013 Cited by PubMed: 23704982 DOI: 10.1371/journal.pone.0064240 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.82 Å)

Structure validation