4HUP

Structure of ricin A chain bound with N-(N-(pterin-7-yl)carbonylglycyl)-L-phenylalanyl)-L-phenylalanine

4HUP の概要

• エントリーDOI: 10.2210/pdb4hup/pdb
• 関連するPDBエントリー: 1BR6 1IFT 1PX8 1RTC 4ESI 4HV3 4HV7 4huo
• 分子名称: Ricin, (2S)-2-[[(2S)-2-[2-[(2-azanyl-4-oxidanylidene-1H-pteridin-7-yl)carbonylamino]ethanoylamino]-3-phenyl-propanoyl]amino]-3-phenyl-propanoic acid, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: ricin, protein-ligand complex, pterin, hydrolase-hydrolase inhibitor complex, toxin, hydrolase, ribosome-inactivating protein, n-glycosidase, hydrolase/hydrolase inhibitor
• 由来する生物種: Ricinus communis (Castor bean)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 30895.55

構造登録者

Jasheway, K.R.,Monzingo, A.F.,Saito, R.,Pruet, J.M.,Manzano, L.A.,Wiget, P.A.,Anslyn, E.V.,Robertus, J.D. (登録日: 2012-11-02, 公開日: 2012-12-26, 最終更新日: 2023-09-20)

• 主引用文献: Saito, R.,Pruet, J.M.,Manzano, L.A.,Jasheway, K.,Monzingo, A.F.,Wiget, P.A.,Kamat, I.,Anslyn, E.V.,Robertus, J.D.; Peptide-conjugated pterins as inhibitors of ricin toxin A.; J.Med.Chem., 56:320-329, 2013; PubMed: 23214944; DOI: 10.1021/jm3016393

実験手法

X-RAY DIFFRACTION (1.699 Å)