4HV7

Structure of ricin A chain bound with N-(N-(pterin-7-yl)carbonylglycyl)glycine

Summary for 4HV7

Entry DOI	10.2210/pdb4hv7/pdb
Related	1BR6 1IFT 1PX8 1PX9 1RTC 4ESI 4HV3 4huo 4hup
Descriptor	Ricin, 2-[2-[(2-azanyl-4-oxidanylidene-1H-pteridin-7-yl)carbonylamino]ethanoylamino]ethanoic acid, SULFATE ION, ... (5 entities in total)
Functional Keywords	ricin, protein-ligand complex, pterin, hydrolase-hydrolase inhibitor complex, toxin, hydrolase, ribosome-inactivating protein, n-glycosidase, hydrolase/hydrolase inhibitor
Biological source	Ricinus communis (Castor bean)
Total number of polymer chains	1
Total formula weight	30458.13
Authors	Jasheway, K.R.,Monzingo, A.F.,Saito, R.,Pruet, J.M.,Manzano, L.A.,Wiget, P.A.,Anslyn, E.V.,Robertus, J.D. (deposition date: 2012-11-05, release date: 2012-12-26, Last modification date: 2023-09-20)
Primary citation	Saito, R.,Pruet, J.M.,Manzano, L.A.,Jasheway, K.,Monzingo, A.F.,Wiget, P.A.,Kamat, I.,Anslyn, E.V.,Robertus, J.D. Peptide-conjugated pterins as inhibitors of ricin toxin A. J.Med.Chem., 56:320-329, 2013 Cited by PubMed: 23214944 DOI: 10.1021/jm3016393 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.869 Å)

Structure validation