4HNF
Crystal structure of ck1d in complex with pf4800567
Summary for 4HNF
| Entry DOI | 10.2210/pdb4hnf/pdb |
| Related | 3UYS 3UYT 3UZP 4HNI 4HOK |
| Descriptor | Casein kinase I isoform delta, 3-[(3-chlorophenoxy)methyl]-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (3 entities in total) |
| Functional Keywords | ck1d, kinase, inhibitor, pf4800567, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: P48730 |
| Total number of polymer chains | 2 |
| Total formula weight | 69420.94 |
| Authors | Huang, X.,Long, A.M.,Zhao, H. (deposition date: 2012-10-19, release date: 2012-11-14, Last modification date: 2024-02-28) |
| Primary citation | Long, A.M.,Zhao, H.,Huang, X. Structural basis for the potent and selective inhibition of casein kinase 1 epsilon. J.Med.Chem., 55:10307-10311, 2012 Cited by PubMed: 23106386DOI: 10.1021/jm301336n PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.07 Å) |
Structure validation
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