4HLS

Crystal structure of mutant rabbit PRP 121-230 (S170N)

Summary for 4HLS

Related4HMM 4HMR
DescriptorMajor prion protein, CHLORIDE ION, SODIUM ION, ... (5 entities in total)
Functional Keywordsprp, prion, membrane, membrane protein
Biological sourceOryctolagus cuniculus (European rabbit,Japanese white rabbit,domestic rabbit,rabbits)
Cellular locationCell membrane; Lipid-anchor, GPI-anchor (By similarity) Q95211
Total number of polymer chains2
Total molecular weight31019.04
Authors
Sweeting, B.,Chakrabartty, A.,Pai, E.F. (deposition date: 2012-10-17, release date: 2013-05-15, Last modification date: 2013-05-22)
Primary citation
Sweeting, B.,Brown, E.,Khan, M.Q.,Chakrabartty, A.,Pai, E.F.
N-Terminal Helix-Cap in alpha-Helix 2 Modulates beta-State Misfolding in Rabbit and Hamster Prion Proteins.
Plos One, 8:e63047-e63047, 2013
PubMed: 23675452 (PDB entries with the same primary citation)
DOI: 10.1371/journal.pone.0063047
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.45 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.180703.2%3.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload