4HLS
Crystal structure of mutant rabbit PRP 121-230 (S170N)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Major prion protein | polymer | 132 | 15267.0 | 2 | UniProt (Q95211) Pfam (PF00377) In PDB | Oryctolagus cuniculus (European rabbit Japanese white rabbit domestic rabbit rabbits) | PrP, PrP27-30, PrP33-35C |
2 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
3 | A, B | SODIUM ION | non-polymer | 23.0 | 6 | Chemie (NA) | |||
4 | B | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
5 | water | water | 18.0 | 181 | Chemie (HOH) |
Sequence modifications
A, B: 120 - 230 (UniProt: Q95211)
PDB | External Database | Details |
---|---|---|
Met 99 | - | expression tag |
Gly 100 | - | expression tag |
Ser 101 | - | expression tag |
Ser 102 | - | expression tag |
His 103 | - | expression tag |
His 104 | - | expression tag |
His 105 | - | expression tag |
His 106 | - | expression tag |
His 107 | - | expression tag |
His 108 | - | expression tag |
Ser 109 | - | expression tag |
Ser 110 | - | expression tag |
Gly 111 | - | expression tag |
Leu 112 | - | expression tag |
Val 113 | - | expression tag |
Pro 114 | - | expression tag |
Arg 115 | - | expression tag |
Gly 116 | - | expression tag |
Ser 117 | - | expression tag |
His 118 | - | expression tag |
Met 119 | - | expression tag |
Asn 170 | Ser 169 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 30533.9 | |
Non-Polymers* | Number of molecules | 11 |
Total formula weight | 485.1 | |
All* | Total formula weight | 31019.0 |