4HKQ
XMRV reverse transcriptase in complex with RNA/DNA hybrid
Summary for 4HKQ
Entry DOI | 10.2210/pdb4hkq/pdb |
Descriptor | Reverse transcriptase/ribonuclease H p80, RNA (5'-R(*AP*AP*CP*AP*GP*AP*GP*UP*GP*CP*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*CP*CP*AP*U)-3'), DNA (5'-D(*TP*GP*GP*AP*AP*TP*CP*A*GP*GP*TP*GP*TP*CP*GP*CP*AP*CP*TP*CP*TP*G)-3'), ... (4 entities in total) |
Functional Keywords | protein-dna-rna complex, reverse transcription, transcription-rna-dna complex, transcription/rna/dna |
Biological source | Xenotropic MuLV-related virus (XMRV) More |
Cellular location | Gag-Pol polyprotein: Host cell membrane; Lipid-anchor (Potential). Matrix protein p15: Virion (Potential). Capsid protein p30: Virion (Potential). Nucleocapsid protein p10: Virion (Potential): A1Z651 |
Total number of polymer chains | 3 |
Total formula weight | 90967.72 |
Authors | Nowak, E.,Potrzebowski, W.,Konarev, P.V.,Rausch, J.W.,Bona, M.K.,Svergun, D.I.,Bujnicki, J.M.,Le Grice, S.F.J.,Nowotny, M. (deposition date: 2012-10-15, release date: 2013-02-20, Last modification date: 2023-11-08) |
Primary citation | Nowak, E.,Potrzebowski, W.,Konarev, P.V.,Rausch, J.W.,Bona, M.K.,Svergun, D.I.,Bujnicki, J.M.,Le Grice, S.F.,Nowotny, M. Structural analysis of monomeric retroviral reverse transcriptase in complex with an RNA/DNA hybrid Nucleic Acids Res., 41:3874-3887, 2013 Cited by PubMed: 23382176DOI: 10.1093/nar/gkt053 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.04 Å) |
Structure validation
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