4HKQ

XMRV reverse transcriptase in complex with RNA/DNA hybrid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Reverse transcriptase/ribonuclease H p80	polymer	681	76202.5	1	UniProt (A1Z651) Pfam (PF00078) Pfam (PF17919) Pfam (PF00075)	Xenotropic MuLV-related virus (XMRV)	RT
2	B (E)	RNA (5'-R(*AP*AP*CP*AP*GP*AP*GP*UP*GP*CP*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*CP*CP*AP*U)-3')	polymer	25	7981.8	1
3	C (F)	DNA (5'-D(*TP*GP*GP*AP*AP*TP*CP*A*GP*GP*TP*GP*TP*CP*GP*CP*AP*CP*TP*CP*TP*G)-3')	polymer	22	6783.4	1
4	D, E, F (A, E, F)	water	water		18.0	37	Chemie (HOH)

Sequence modifications

A: 1 - 671 (UniProt: A1Z651)

PDB	External Database	Details
Met -9	-	expression tag
Ser -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Ser -1	-	expression tag
Ala 0	-	expression tag
Asn 583	Asp 1240	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	90967.7
All*	Total formula weight	90967.7

*Water molecules are not included.