4H3K
Crystal structure of a ternary complex of human symplekin NTD, human Ssu72 and a RNA polymerase II CTD peptide phosphorylated at Ser-2, Ser-5 and Ser-7
Summary for 4H3K
Entry DOI | 10.2210/pdb4h3k/pdb |
Related | 3O2Q 4H3H |
Descriptor | Symplekin, RNA polymerase II subunit A C-terminal domain phosphatase SSU72, Hexapeptide, ... (5 entities in total) |
Functional Keywords | heat repeat, phosphatase, rna polymerase ii, hydrolase |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm, cytoskeleton: Q92797 Nucleus: Q9NP77 |
Total number of polymer chains | 5 |
Total formula weight | 130221.48 |
Authors | |
Primary citation | Xiang, K.,Manley, J.L.,Tong, L. An unexpected binding mode for a Pol II CTD peptide phosphorylated at Ser7 in the active site of the CTD phosphatase Ssu72. Genes Dev., 26:2265-2270, 2012 Cited by PubMed: 23070812DOI: 10.1101/gad.198853.112 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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