4H3K
Crystal structure of a ternary complex of human symplekin NTD, human Ssu72 and a RNA polymerase II CTD peptide phosphorylated at Ser-2, Ser-5 and Ser-7
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, D | Symplekin | polymer | 351 | 39647.0 | 2 | UniProt (Q92797) Pfam (PF11935) In PDB | Homo sapiens (human) | |
2 | B, E | RNA polymerase II subunit A C-terminal domain phosphatase SSU72 | polymer | 214 | 24758.8 | 2 | UniProt (Q9NP77) Pfam (PF04722) In PDB | Homo sapiens (human) | CTD phosphatase SSU72 |
3 | F | Hexapeptide | polymer | 10 | 1315.0 | 1 | |||
4 | B | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
5 | water | water | 18.0 | 113 | Chemie (HOH) |
Sequence modifications
A, D: 30 - 360 (UniProt: Q92797)
B, E: 1 - 194 (UniProt: Q9NP77)
PDB | External Database | Details |
---|---|---|
Met 10 | - | EXPRESSION TAG |
Gly 11 | - | EXPRESSION TAG |
Ser 12 | - | EXPRESSION TAG |
Ser 13 | - | EXPRESSION TAG |
His 14 | - | EXPRESSION TAG |
His 15 | - | EXPRESSION TAG |
His 16 | - | EXPRESSION TAG |
His 17 | - | EXPRESSION TAG |
His 18 | - | EXPRESSION TAG |
His 19 | - | EXPRESSION TAG |
Ser 20 | - | EXPRESSION TAG |
Ser 21 | - | EXPRESSION TAG |
Gly 22 | - | EXPRESSION TAG |
Leu 23 | - | EXPRESSION TAG |
Val 24 | - | EXPRESSION TAG |
Pro 25 | - | EXPRESSION TAG |
Arg 26 | - | EXPRESSION TAG |
Gly 27 | - | EXPRESSION TAG |
Ser 28 | - | EXPRESSION TAG |
His 29 | - | EXPRESSION TAG |
PDB | External Database | Details |
---|---|---|
Met -19 | - | EXPRESSION TAG |
Gly -18 | - | EXPRESSION TAG |
Ser -17 | - | EXPRESSION TAG |
Ser -16 | - | EXPRESSION TAG |
His -15 | - | EXPRESSION TAG |
His -14 | - | EXPRESSION TAG |
His -13 | - | EXPRESSION TAG |
His -12 | - | EXPRESSION TAG |
His -11 | - | EXPRESSION TAG |
His -10 | - | EXPRESSION TAG |
Ser -9 | - | EXPRESSION TAG |
Ser -8 | - | EXPRESSION TAG |
Gly -7 | - | EXPRESSION TAG |
Leu -6 | - | EXPRESSION TAG |
Val -5 | - | EXPRESSION TAG |
Pro -4 | - | EXPRESSION TAG |
Arg -3 | - | EXPRESSION TAG |
Gly -2 | - | EXPRESSION TAG |
Ser -1 | - | EXPRESSION TAG |
His 0 | - | EXPRESSION TAG |
Ser 12 | Cys 12 | ENGINEERED MUTATION |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 130126.5 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 95.0 | |
All* | Total formula weight | 130221.5 |