4GNK

Crystal structure of Galphaq in complex with full-length human PLCbeta3

4GNK の概要

• エントリーDOI: 10.2210/pdb4gnk/pdb
• 分子名称: Guanine nucleotide-binding protein G(q) subunit alpha, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, GUANOSINE-5'-DIPHOSPHATE, ... (8 entities in total)
• 機能のキーワード: gtp-binding protein alpha subunits, phospholipase c beta, coiled-coil domain, ph domain, ef hand, c2 domain, tim barrel domain, phospholipase, gtp hydrolysis, g-protein signaling, membrane targeting, lipase, hydrolase, calcium binding, gtp binding, phospholipids, gtp-binding protein-hydrolase complex, gtp-binding protein/hydrolase
• 由来する生物種: Mus musculus (mouse); 詳細
• 細胞内の位置: Nucleus: P21279; Membrane; Peripheral membrane protein: Q01970 Q01970
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 393280.92

構造登録者

Lyon, A.M.,Tesmer, J.J.G. (登録日: 2012-08-17, 公開日: 2013-02-06, 最終更新日: 2023-09-13)

• 主引用文献: Lyon, A.M.,Dutta, S.,Boguth, C.A.,Skiniotis, G.,Tesmer, J.J.; Full-length G alpha (q)-phospholipase C-beta 3 structure reveals interfaces of the C-terminal coiled-coil domain.; Nat.Struct.Mol.Biol., 20:355-362, 2013; PubMed: 23377541; DOI: 10.1038/nsmb.2497

実験手法

X-RAY DIFFRACTION (4 Å)