4GKO
Crystal structure of the calcium2+-bound human IgE-Fc(epsilon)3-4 bound to its B cell receptor derCD23
Summary for 4GKO
Entry DOI | 10.2210/pdb4gko/pdb |
Related | 1T8C 1T8D 2H2R 2H2T 3H9Y 3HA0 4EZM 4G96 4G9A 4GI0 4GJ0 4GJX 4GK1 |
Descriptor | Ig epsilon chain C region, Low affinity immunoglobulin epsilon Fc receptor, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | immunoglobulin fold lectin, antibody receptor, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane; Single-pass type II membrane protein: P06734 |
Total number of polymer chains | 12 |
Total formula weight | 252576.51 |
Authors | Yuan, D.,Sutton, B.J.,Dhaliwal, B. (deposition date: 2012-08-13, release date: 2013-06-26, Last modification date: 2024-10-09) |
Primary citation | Yuan, D.,Keeble, A.H.,Hibbert, R.G.,Fabiane, S.,Gould, H.J.,McDonnell, J.M.,Beavil, A.J.,Sutton, B.J.,Dhaliwal, B. Ca2+-dependent Structural Changes in the B-cell Receptor CD23 Increase Its Affinity for Human Immunoglobulin E. J.Biol.Chem., 288:21667-21677, 2013 Cited by PubMed: 23775083DOI: 10.1074/jbc.M113.480657 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.3 Å) |
Structure validation
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