4GKO

Crystal structure of the calcium2+-bound human IgE-Fc(epsilon)3-4 bound to its B cell receptor derCD23

4GKO の概要

• エントリーDOI: 10.2210/pdb4gko/pdb
• 関連するPDBエントリー: 1T8C 1T8D 2H2R 2H2T 3H9Y 3HA0 4EZM 4G96 4G9A 4GI0 4GJ0 4GJX 4GK1
• 分子名称: Ig epsilon chain C region, Low affinity immunoglobulin epsilon Fc receptor, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: immunoglobulin fold lectin, antibody receptor, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cell membrane; Single-pass type II membrane protein: P06734
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 252576.51

構造登録者

Yuan, D.,Sutton, B.J.,Dhaliwal, B. (登録日: 2012-08-13, 公開日: 2013-06-26, 最終更新日: 2024-10-09)

• 主引用文献: Yuan, D.,Keeble, A.H.,Hibbert, R.G.,Fabiane, S.,Gould, H.J.,McDonnell, J.M.,Beavil, A.J.,Sutton, B.J.,Dhaliwal, B.; Ca2+-dependent Structural Changes in the B-cell Receptor CD23 Increase Its Affinity for Human Immunoglobulin E.; J.Biol.Chem., 288:21667-21677, 2013; PubMed: 23775083; DOI: 10.1074/jbc.M113.480657

実験手法

X-RAY DIFFRACTION (3.3 Å)