4G5R

Structure of LGN GL4/Galphai3 complex

4G5R の概要

関連するPDBエントリー4G5O 4G5Q 4G5S
分子名称Guanine nucleotide-binding protein G(k) subunit alpha, G-protein-signaling modulator 2, GUANOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
機能のキーワードgalphai, goloco, galpha signaling, asymmetric cell division, cell cycle-signaling protein complex, cell cycle/signaling protein
由来する生物種Homo sapiens (human)
詳細
細胞内の位置Cytoplasm P08754
Cytoplasm (By similarity) Q8VDU0
ポリマー鎖数8
分子量合計166839.76
構造登録者
Jia, M.,Li, J.,Zhu, J.,Wen, W.,Zhang, M.,Wang, W. (登録日: 2012-07-18, 公開日: 2012-09-05)
主引用文献
Jia, M.,Li, J.,Zhu, J.,Wen, W.,Zhang, M.,Wang, W.
Crystal Structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Galphai subunits in G-coupled heterotrimeric proteins
To be Published,
実験手法
X-RAY DIFFRACTION (3.481 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.248100.9%8.3%3.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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