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4FVN

Carbonic Anhydrase II in complex with N-(tetrahydropyrimidin-2(1H)-ylidene)sulfuric diamide

Summary for 4FVN
Entry DOI10.2210/pdb4fvn/pdb
Related4FPT 4FRC 4FU5 4FVO
DescriptorCarbonic anhydrase 2, MERCURIBENZOIC ACID, ZINC ION, ... (6 entities in total)
Functional Keywords10 stranded twisted beta-sheets, lyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: P00918
Total number of polymer chains1
Total formula weight30010.65
Authors
Di Pizio, A.,Heine, A.,Klebe, G. (deposition date: 2012-06-29, release date: 2013-07-17, Last modification date: 2023-09-13)
Primary citationDi Pizio, A.,Schulze Wischeler, J.,Haake, M.,Heine, A.,Supuran, C.,Klebe, G.
HIgh resolution crystal structures of Carbonic Anhydrase II in complex with novel sulfamide binders
To be Published,
Experimental method
X-RAY DIFFRACTION (1.05 Å)
Structure validation

221051

數據於2024-06-12公開中

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