4FLC
Structural and Biochemical Characterization of Human Adenylosuccinate Lyase (ADSL) and the R303C ADSL Deficiency Associated Mutation
Summary for 4FLC
| Entry DOI | 10.2210/pdb4flc/pdb |
| Related | 2J91 2VD6 |
| Descriptor | Adenylosuccinate lyase (2 entities in total) |
| Functional Keywords | purine biosynthesis, lyase, disease mutation, purine metabolism |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 4 |
| Total formula weight | 220878.03 |
| Authors | Deaton, M.K.,Ray, S.P.,Capodagli, G.C.,Calkins, L.A.F.,Sawle, L.,Ghosh, K.,Patterson, D.,Pegan, S.D. (deposition date: 2012-06-14, release date: 2012-08-01, Last modification date: 2023-09-13) |
| Primary citation | Ray, S.P.,Deaton, M.K.,Capodagli, G.C.,Calkins, L.A.,Sawle, L.,Ghosh, K.,Patterson, D.,Pegan, S.D. Structural and Biochemical Characterization of Human Adenylosuccinate Lyase (ADSL) and the R303C ADSL Deficiency-Associated Mutation. Biochemistry, 51:6701-6713, 2012 Cited by PubMed: 22812634DOI: 10.1021/bi300796y PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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