4FLC
Structural and Biochemical Characterization of Human Adenylosuccinate Lyase (ADSL) and the R303C ADSL Deficiency Associated Mutation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Adenylosuccinate lyase | polymer | 487 | 55219.5 | 4 | UniProt (P30566) Pfam (PF00206) Pfam (PF10397) In PDB | Homo sapiens (human) | ASL, Adenylosuccinase, ASase |
| 2 | water | water | 18.0 | 144 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 484 (UniProt: P30566)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Arg 63 | Gln 63 | conflict |
| Cys 303 | Arg 303 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 220878.0 | |
| All* | Total formula weight | 220878.0 |
