4FKY

Crystal structure of nucleoside diphosphate kinase B from Trypanosoma brucei bound to GTP

Summary for 4FKY

• Entry DOI: 10.2210/pdb4fky/pdb
• Related: 4F36 4F4A 4FKX
• Descriptor: Nucleoside diphosphate kinase, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: structural genomics, niaid, national institute of allergy and infectious diseases, seattle structural genomics center for infectious disease, ssgcid, african trypanosomiasis, african sleeping sickness, ntp biosynthesis, ndp, transferase
• Biological source: Trypanosoma brucei brucei
• Total number of polymer chains: 3
• Total formula weight: 55251.98

Authors

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2012-06-13, release date: 2012-06-27, Last modification date: 2026-03-18)

• Primary citation: Makori, P.,Boeckman, M.P.,David, H.S.,Payne, F.,Gatling, M.,Greer, C.,Hayes, D.,Jefferson, A.,Maxwell, M.,Smith, C.,Watson, J.,Williams, L.,Barkley, J.,Pepper, C.,Zininga, T.,Subramanian, S.,Abramov, A.,Gardberg, A.S.,Edwards, T.E.,Staker, B.L.,Stewart, L.J.,Myler, P.J.,Asojo, O.A.,Jeje, O.,Fanucchi, S.,Achilonu, I.,Smith, C.L.,Chakafana, G.; Structural and Functional Analyses of Trypanosoma brucei Nucleoside Diphosphate Kinase; Acs Omega, 2026; DOI: 10.1021/acsomega.5c11614

Experimental method

X-RAY DIFFRACTION (1.95 Å)