4FKO

Crystal structure of the cdk2 in complex with thiazolylpyrimidine inhibitor

Summary for 4FKO

• Entry DOI: 10.2210/pdb4fko/pdb
• Related: 4EK3 4EK4 4EK5 4EK6 4EK8 4FKG 4FKI 4FKJ 4FKL 4FKP 4FKQ 4FKR 4FKS 4FKT 4FKU 4FKV 4FKW
• Descriptor: Cyclin-dependent kinase 2, 2-chloro-N~4~-[4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-yl]-N~1~,N~1~-dimethylbenzene-1,4-diamine, ACETATE ION, ... (4 entities in total)
• Functional Keywords: alpha and beta protein (a+b), transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm, cytoskeleton, centrosome: P24941
• Total number of polymer chains: 1
• Total formula weight: 34421.45

Authors

Kang, Y.N.,Stuckey, J.A. (deposition date: 2012-06-13, release date: 2013-05-08, Last modification date: 2023-09-13)

• Primary citation: Kang, Y.N.,Stuckey, J.A.; Crystal structure of the cdk2 in complex with thiazolylpyrimidine inhibitor; To be Published,

Experimental method

X-RAY DIFFRACTION (1.55 Å)