4FGU
Crystal structure of prolegumain
Summary for 4FGU
Entry DOI | 10.2210/pdb4fgu/pdb |
Related | 4aw9 4awa 4awb |
Descriptor | Legumain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | cysteine protease, aep, asparaginyl endopeptidase, substrate specificity, mhcii, antigen processing, proenzyme, cancer, lysosomal, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 99702.16 |
Authors | Dall, E.,Brandstetter, H. (deposition date: 2012-06-05, release date: 2013-07-03, Last modification date: 2020-07-29) |
Primary citation | Dall, E.,Brandstetter, H. Mechanistic and structural studies on legumain explain its zymogenicity, distinct activation pathways, and regulation. Proc.Natl.Acad.Sci.USA, 110:10940-10945, 2013 Cited by PubMed: 23776206DOI: 10.1073/pnas.1300686110 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.9 Å) |
Structure validation
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