4FGU
Crystal structure of prolegumain
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Legumain | polymer | 429 | 49205.5 | 2 | UniProt (Q99538) Pfam (PF01650) Pfam (PF20985) In PDB | Homo sapiens (human) | Asparaginyl endopeptidase, Protease, cysteine 1 |
2 | C, D | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
3 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
4 | water | water | 18.0 | 56 | Chemie (HOH) |
Sequence modifications
A, B: 18 - 433 (UniProt: Q99538)
PDB | External Database | Details |
---|---|---|
Gly 13 | - | expression tag |
Ala 14 | - | expression tag |
Ser 15 | - | expression tag |
Leu 16 | - | expression tag |
Glu 17 | - | expression tag |
Ile 18 | Val 18 | variant |
Gln 272 | Asn 272 | engineered mutation |
Gly 434 | - | expression tag |
Thr 435 | - | expression tag |
His 436 | - | expression tag |
His 437 | - | expression tag |
His 438 | - | expression tag |
His 439 | - | expression tag |
His 440 | - | expression tag |
His 441 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 98410.9 | |
Branched | Number of molecules | 2 |
Total formula weight | 848.8 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 442.4 | |
All* | Total formula weight | 99702.2 |