4FGC

Crystal Structure of Active Site Mutant C55A of Nitrile Reductase QueF, Bound to Substrate PreQ0

Summary for 4FGC

• Entry DOI: 10.2210/pdb4fgc/pdb
• Related: 4F8B
• Descriptor: NADPH-dependent 7-cyano-7-deazaguanine reductase, 2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDINE-5-CARBONITRILE, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: beta barrel, pterin binding fold, tunnel fold, trna modification enzyme, 7-cyano-7-deazaguanine (preq0) binding, nadph binding, oxidoreductase
• Biological source: Bacillus subtilis subsp. subtilis
• Cellular location: Cytoplasm : O31678
• Total number of polymer chains: 5
• Total formula weight: 98200.10

Authors

Stec, B.,Swairjo, M.A. (deposition date: 2012-06-04, release date: 2012-07-11, Last modification date: 2023-09-13)

• Primary citation: Chikwana, V.M.,Stec, B.,Lee, B.W.,de Crecy-Lagard, V.,Iwata-Reuyl, D.,Swairjo, M.A.; Structural basis of biological nitrile reduction.; J.Biol.Chem., 287:30560-30570, 2012; PubMed: 22787148; DOI: 10.1074/jbc.M112.388538

Experimental method

X-RAY DIFFRACTION (2.498 Å)