4FFB

A TOG:alpha/beta-tubulin Complex Structure Reveals Conformation-Based Mechanisms For a Microtubule Polymerase

Summary for 4FFB

Entry DOI	10.2210/pdb4ffb/pdb
Descriptor	Tubulin alpha-1 chain, Tubulin beta chain, Protein STU2, ... (5 entities in total)
Functional Keywords	tubulin fold, heat repeats, cytoskeleton, microtubule, tubulin, tog domain, hydrolase
Biological source	Saccharomyces cerevisiae (Baker's yeast) More
Cellular location	Cytoplasm, cytoskeleton: P09733 P02557 Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body: P46675
Total number of polymer chains	3
Total formula weight	134525.50
Authors	Ayaz, P.,Ye, X.,Huddleston, P.,Brautigam, C.A.,Rice, L.M. (deposition date: 2012-05-31, release date: 2012-08-15, Last modification date: 2023-09-13)
Primary citation	Ayaz, P.,Ye, X.,Huddleston, P.,Brautigam, C.A.,Rice, L.M. A TOG: alpha beta-tubulin complex structure reveals conformation-based mechanisms for a microtubule polymerase. Science, 337:857-860, 2012 Cited by PubMed: 22904013 DOI: 10.1126/science.1221698 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.882 Å)

Structure validation