4FFB
A TOG:alpha/beta-tubulin Complex Structure Reveals Conformation-Based Mechanisms For a Microtubule Polymerase
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Tubulin alpha-1 chain | polymer | 447 | 49853.9 | 1 | UniProt (P09733) Pfam (PF00091) Pfam (PF03953) In PDB | Saccharomyces cerevisiae (Baker's yeast) | |
2 | B | Tubulin beta chain | polymer | 463 | 51910.5 | 1 | UniProt (P02557) Pfam (PF00091) Pfam (PF03953) In PDB | Saccharomyces cerevisiae (Baker's yeast) | Beta-tubulin |
3 | C | Protein STU2 | polymer | 278 | 31666.2 | 1 | UniProt (P46675) Pfam (PF21041) In PDB | Saccharomyces cerevisiae (Baker's yeast) | Suppressor of tubulin 2 |
4 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
5 | A, B | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) |
Sequence modifications
B: 1 - 457 (UniProt: P02557)
C: 1 - 272 (UniProt: P46675)
PDB | External Database | Details |
---|---|---|
Arg 175 | Thr 175 | engineered mutation |
Arg 179 | Val 179 | engineered mutation |
His 458 | - | expression tag |
His 459 | - | expression tag |
His 460 | - | expression tag |
His 461 | - | expression tag |
His 462 | - | expression tag |
His 463 | - | expression tag |
PDB | External Database | Details |
---|---|---|
His 273 | - | expression tag |
His 274 | - | expression tag |
His 275 | - | expression tag |
His 276 | - | expression tag |
His 277 | - | expression tag |
His 278 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 133430.5 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1095.0 | |
All* | Total formula weight | 134525.5 |