4FDC
Crystal structure of the E493V mutant of human apoptosis inducing factor (AIF)
Summary for 4FDC
Entry DOI | 10.2210/pdb4fdc/pdb |
Related | 1M6I |
Descriptor | Apoptosis-inducing factor 1, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE (2 entities in total) |
Functional Keywords | rossmann fold, mitochondrion, appoptosis, oxidoreductase, apoptosis |
Biological source | Homo sapiens (human) |
Cellular location | Mitochondrion intermembrane space: O95831 |
Total number of polymer chains | 1 |
Total formula weight | 56837.26 |
Authors | Sevrioukova, I.F. (deposition date: 2012-05-27, release date: 2012-10-17, Last modification date: 2023-09-13) |
Primary citation | Rinaldi, C.,Grunseich, C.,Sevrioukova, I.F.,Schindler, A.,Horkayne-Szakaly, I.,Lamperti, C.,Landoure, G.,Kennerson, M.L.,Burnett, B.G.,Bonnemann, C.,Biesecker, L.G.,Ghezzi, D.,Zeviani, M.,Fischbeck, K.H. Cowchock syndrome is associated with a mutation in apoptosis-inducing factor. Am.J.Hum.Genet., 91:1095-1102, 2012 Cited by PubMed: 23217327DOI: 10.1016/j.ajhg.2012.10.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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