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4FDC

Crystal structure of the E493V mutant of human apoptosis inducing factor (AIF)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(B)
Apoptosis-inducing factor 1, mitochondrialpolymer51456051.71UniProt (O95831)
Pfam (PF00070)
Pfam (PF14721)
Homo sapiens (human)Programmed cell death protein 8
2B
(B)
FLAVIN-ADENINE DINUCLEOTIDEnon-polymer785.51Chemie (FAD)
Sequence modifications
B: 103 - 613 (UniProt: O95831)
PDBExternal DatabaseDetails
Val 493Glu 493engineered mutation
Leu 614-expression tag
Val 615-expression tag
Pro 616-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight56051.7
Non-Polymers*Number of molecules1
Total formula weight785.5
All*Total formula weight56837.3
*Water molecules are not included.

239803

PDB entries from 2025-08-06

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