4F5D
ERIS/STING in complex with ligand
Summary for 4F5D
Entry DOI | 10.2210/pdb4f5d/pdb |
Related | 4F5E |
Descriptor | Transmembrane protein 173, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | receptor, immune system |
Biological source | Homo sapiens (human) |
Cellular location | Endoplasmic reticulum membrane ; Multi-pass membrane protein : Q86WV6 |
Total number of polymer chains | 2 |
Total formula weight | 57985.77 |
Authors | Huang, Y.H.,Liu, X.Y.,Su, X.D. (deposition date: 2012-05-13, release date: 2012-06-27, Last modification date: 2024-03-20) |
Primary citation | Huang, Y.H.,Liu, X.Y.,Du, X.X.,Jiang, Z.F.,Su, X.D. The structural basis for the sensing and binding of cyclic di-GMP by STING Nat.Struct.Mol.Biol., 19:728-730, 2012 Cited by PubMed: 22728659DOI: 10.1038/nsmb.2333 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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