4F28

The Crystal Structure of a Human MitoNEET mutant with Met 62 Replaced by a Gly

4F28 の概要

• エントリーDOI: 10.2210/pdb4f28/pdb
• 関連するPDBエントリー: 2QH7 3EW0 3LPQ 4EZF 4F1E 4F2C
• 分子名称: CDGSH iron-sulfur domain-containing protein 1, FE2/S2 (INORGANIC) CLUSTER (3 entities in total)
• 機能のキーワード: 2fe-2s proteins, membrane, signal-anchor, transmembrane metal binding protein, protein frustration, mitochondrial outer membrane, metal binding protein
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Mitochondrion outer membrane; Single-pass type III membrane protein: Q9NZ45
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 18100.01

構造登録者

Baxter, E.L.,Zuris, J.A.,Wang, C.,Axelrod, H.L.,Cohen, A.E.,Paddock, M.L.,Nechushtai, R.,Onuchic, J.N.,Jennings, P.A. (登録日: 2012-05-07, 公開日: 2012-12-26, 最終更新日: 2024-02-28)

• 主引用文献: Baxter, E.L.,Zuris, J.A.,Wang, C.,Vo, P.L.,Axelrod, H.L.,Cohen, A.E.,Paddock, M.L.,Nechushtai, R.,Onuchic, J.N.,Jennings, P.A.; Allosteric control in a metalloprotein dramatically alters function.; Proc.Natl.Acad.Sci.USA, 110:948-953, 2013; PubMed: 23271805; DOI: 10.1073/pnas.1208286110

実験手法

X-RAY DIFFRACTION (1.55 Å)