4F0A

Crystal structure of XWnt8 in complex with the cysteine-rich domain of Frizzled 8

4F0A の概要

• エントリーDOI: 10.2210/pdb4f0a/pdb
• 関連するPDBエントリー: 1IJY
• 分子名称: Frizzled-8, Protein Wnt-8, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: wnt signaling, ligand-receptor complex, wnt, frizzled, fatty acid acylation, glycosylation, signaling protein
• 由来する生物種: Mus musculus (mouse); 詳細
• 細胞内の位置: Membrane; Multi-pass membrane protein: Q61091; Secreted, extracellular space, extracellular matrix: P28026
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 52603.69

構造登録者

Janda, C.Y.,Waghray, D.,Levin, A.M.,Thomas, C.,Garcia, K.C. (登録日: 2012-05-03, 公開日: 2012-06-13, 最終更新日: 2020-07-29)

• 主引用文献: Janda, C.Y.,Waghray, D.,Levin, A.M.,Thomas, C.,Garcia, K.C.; Structural basis of Wnt recognition by Frizzled.; Science, 337:59-64, 2012; PubMed: 22653731; DOI: 10.1126/science.1222879

実験手法

X-RAY DIFFRACTION (3.25 Å)